2013, Volume 19, Issue 1

Sexually Transmitted Infections in the Residual Forces Participating in Military Missions - Diagnostic and Prophylactic Proceedings

Maria GOŁĘBIOWSKA-WAWRZYNIAK¹, Katarzyna MARKIEWICZ¹, Tomasz MACIEJEWSKI¹, Artur JAKIMIUK², Olaf TRUSZCZYŃSKI³, Tomasz KOZICKI³, Andrzej MODRZEWSKI³, Agata KOZAR¹, Zbigniew WAWRZYNIAK⁴, Krzysztof RYTWIŃSKI¹
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¹Institute of Mother and Child
²Central Clinical Hospital of the Ministry of Interior
³Military Institute of Aviaton Medicine
⁴Medical University of Warsaw


Autor korenspondencyjny: Maria GOŁĘBIOWSKA-WAWRZYNIAK; Institute of Mother and Child; email: zaklad.immunologii[at]imid.med.pl

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Streszczenie

Introduction. The number of women on military missions has been increasing recently. While on military missions, they live in an isolated group dominated by men. Such groups consist of young, sexually active individuals, thus increasing the risk of sexually transmitted infections. Methods. Medical examinations were performed on various residual forces (military, police, security guards) totaling 579 individuals, up to 35 years of age (172 women and 407 men). Subjects qualified for the study were divided into 2 groups. Group I consisted of persons who remained in the country. Group II included persons stationed on military missions abroad. A total of 306 soldiers from this group participated in Study 1. Study 2 (clinical and laboratory) was carried out 6-12 months later on 52 patients from Group II and 119 patients from Group I (84 women and 87 men). Additionally, transcription of HPV genes E6 and E7 (with high oncogenic risk) was carried out in the group made up of 200 women. Laboratory examinations included: peripheral blood morphology, lymphocyte subpopulations by l ow cytometry method (CD45, CD3, CD19, CD4, CD8 markers and NK cells CD16+CD56 markers), IL-2, IL-4, TNF-alfa, IFN-gamma, IL-18 concentration by flow cytometry method. IgG, IgA, IgM concentration by turbidimetric method and IgE concentration by ELISA method. Determination of anti-HSV-2, HIV and Chlamydia trachomatis antibodies by ELISA method. For the assessment of HPV infections, DNA extracted from cervical squamous epithelial cells was tested by PCR, HPV genotype was examined via the expression of E6 and E7 oncogenes of HPV 16,18,33,35,45 strains by real-time NASBA. Results. In a group of 579 individuals, HPV infection was confirmed in 41 men (10%) and 24 women (14.8%). HSV-2 test was positive in 17 persons: 6 men (1.5%) and 11 women (6.4%). Chlamydia trachomatis infection was confirmed in 10 patients: 6 men (1.5%) and 4 women (2.3%). HIV test was negative. Following a period of 6 months, further tests were conducted on 171 individuals from a group of 579 subjects. HPV infection was detected in 22 individuals (12.9%) - 13 men (14.9%) and 9 women (10.8%). HSV-2 was detected in 11 cases - 2 men (2.3%) and 9 women (10.7%). Chlamydia trachomatis was detected in 4 persons - 2 men (2.3%) and 2 women (2.4%). Immunological parameters in the examined groups were without significant variations. Conclusions. 1) The frequency of HPV, HIV, HSV-2 and Chlamydia trachomatis infections was lower in the residual forces than in the general Polish population or the rates published in medical publications throughout the world. 2)The investigation did not find an increase in the frequency of HSV-2, Chlamydia trachomatis, HIV and HPV infections in the groups of individuals on military missions abroad, as compared to those who remained in the country.

Słowa kluczowe

infections, HSV-2, Chlamydia trachomatis, HIV, HPV, immunodefi ciency