2024, Volume 30, Issue 3

ALBUMIN/CREATININE RATIO IN A SINGLE URINE SAMPLE (ACR) AS AN EARLY INDICATOR OF KIDNEY DAMAGE IN TYPE 2 DIABETES

SZYMON NAZAR¹
-------------------------------------------------------------------------------------------------
¹Department of Internal Disease, Cardiology and Metabolic Disorders, Military Institute of Aviation Medicine


Autor korenspondencyjny: SZYMON NAZAR; Department of Internal Disease, Cardiology and Metabolic Disorders, Military Institute of Aviation Medicine; email: s.nazar@wiml.waw.pl

Streszczenie

Abstract: Type 2 diabetes mellitus (DM type 2) is associated with numerous organ complications. One of the pathophysiological mechanisms of this disease is damage to the renal filtration barrier, which can lead to increased protein excretion in the urine, an early marker of kidney function impairment.
Detecting albuminuria is crucial in diagnosis and prevention, as its presence, even with normal estimated glomerular filtration rate (eGFR), indicates a higher risk of progression and faster deterioration of kidney function. This approach speeds up the start of treatment and may prevent further kidney damage. According to a review of the available literature, measuring the albumin/creatinine ratio in a single urine sample is a sensitive method for detecting albuminuria and is comparable to the results of 24-hour urine collections, making it a practical tool for risk assessment, diagnosis, and prevention of complications in diabetic kidney disease.

Słowa kluczowe

diabetic kidney disease, microalbuminuria, urine albumin/creatinine ratio